Latest Research Preprints - Life Science Network

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This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 06 Aug 2026

In vitro and in silico characterization of competitive inhibition and repression of DUX4 target gene activation as a therapeutic approach for facioscapulohumeral muscular dystrophy (FSHD)

by Hoffmann, H. M., Finkelstein, A., Geremew, A., Xu, K., Chiprez Meza, V., Mohanty, A., Velasquez, M. F., Liu, M., Engel, A., Kyriakakis, P.
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Created 03 Aug 2026

An alphabet of allostery: a transferable transfer entropy contact patterns predicts allosteric-site character and conformational rewiring

by Hacisuleyman, A.
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Created 26 Jul 2026

Concept-Level Semantic Representations Remain Decodable in Chronic Post-Stroke Aphasia

by Swiderski, A. M., Bohland, J. W., Johnson, J. P., Dickey, M. W., Wilson, S. M., Hula, W. D.
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Created 27 Jul 2026

Anti-Z-NA antibodies can distinguish accessible Z-form states across DNA, RNA, and DNA-RNA substrates

by Chin, D., Luo, Y., He, Z., Yin, C., Williams, R., Dröge, P., Balachandran, S., Luo, D.
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Created 07 Aug 2026

Deletion of the ribosomal protein gene rpmJ activates zntA transcription through a translation-dependent mechanism in Escherichia coli

by Shirakawa, R., Ishikawa, K., Furuta, K., Kaito, C.
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Created 08 Aug 2026

ClinOracle: Hierarchical AI Prediction of Target Binding and Patient-Derived Functional Activity Across Diverse Therapeutic Targets

by Abdel-Rahman, S., Gabr, M.
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Created 05 Aug 2026

Gut-Associated Metabolites (GAMs) revitalize dysfunctional CD8⁺ T lymphocytes in Osteosarcoma

by SAPRA, L., Bhardwaj, A., Paladhi, A., Farhat, A., Kaur, T., Kaur, S. P., Saini, C., Kumar, V. S., Khan, S. A., Srivastava, R. K.
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Created 07 Aug 2026

Locus-specific transposable element expression drives human hematopoietic stem cell disease pathophysiology

by Varesi, A., Dong, S., Gaddoni, C., Kaufmann, K. B., Wong, T., Merelli, I., Zeng, A. G. X., McLeod, J., Jin, L., di Biasio, I., Novitzky-Basso, I., Mattson, J., Xie, S. Z., Li, B., Ferrari, S., Dick, J. E.
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Created 26 Jul 2026

Lineage-specific regulation and RNA-associated functions of SATB1 in mature B-cells

by Frayssinhes, J.-Y. A., Meriot, L., Marchiol, T., Pinault, E., Forne, T., Spilianakis, C., PINAUD, E., Le Noir, S.
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Created 08 Aug 2026

tinyRNA-seq: An optimized approach to sequencing tiny RNAs and primitive RNA genomes

by Colville, B. W. F., Zhao, J., Hade, L., Szostak, J. W.
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